3117 Ch-01.qxd

The Cytidine Analog Fluorocyclopentenylcytosine (RX-3117) Is Activated by Uridine-Cytidine Kinase 2

Fluorocyclopentenylcytosine (RX-3117) is an orally available cytidine analog, currently in Phase I clinical trial. RX-3117 has promising antitumor activity in various human tumor xenografts including gemcitabine resistant tumors. RX-3117 is activated by uridine-cytidine kinase (UCK). Since UCK exists in two forms, UCK1 and UCK2, we investigated which form is responsible for RX-3117 phosphorylat...

Inuit health system must move past suicide prevention to "unlock a better reality," conference told.

Deegan Ch 01

01 Focus Pre eclampsia UK:Mise en page 1.qxd

The frequency of PE is of the order of 2 to 7 % in healthy nullipara and 20 to 25 % in the event of a major risk factor. Arterial hypertension is severe in 6 to 15 % of cases. The frequency of eclampsia is low (< 0.1 %), but is the cause of 15 to 20 % of deaths in developed countries. Preventive measures and symptomatic treatments: recovery generally occurs without any after-effects and without...

Research high_EN#01-142.qxd

CMHC then contracted with 10 consulting firms to gather data from apartment buildings across the country. Construction dates of the buildings range from 1920 to 1993.The buildings are from six to 26 storeys in height and from 3,345 m to 26,795 m in size, with a total of 27 to 400 suites per building. The buildings are located in the West Coast, Prairie, Central and Atlantic regions of the count...